Computational Molecular Biology

An introduction to the interdisciplinary field of computational molecular biology. Students are taught the scope and methods of in silico biology, i.e., the application of computational and statistical methods to solving problems in molecular biology. Topics will include homology searching, sequence alignment, molecular phylogenetics, comparative genomics, analysis of gene expression, and predication of macromolecular structures. The course will be taught using a mixed format of lectures and hands-on workshops in a UNIX computer laboratory setting.Knowledge and skills in molecular biology, UNIX programming, and statistics are essential for success in this core course required for bioinformatics-concentration students from all majors.

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